A new “burden-free” study in which study procedures were done as part of routine clinical care showed that two blood pressure meds, chlorthalidone (CTD) and hydrochlorothiazide (HCTZ), were equally effective and safe.  Both drugs decrease blood pressure by decreasing excess fluid in the body. When two medications are approved for use, it can be very helpful to compare them, for example as in this case, to see if one causes more side effects.  The method of building a research study into standard care is described as burden-free because it does not require Veterans to undergo additional visits or interventions and does not require any additional staff.  A win-win.